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Immunohistochemical staining of -SMA (1:2000, Proteintech, Wuhan, China, 14395-1-AP) and collagen I (1:1000, Proteintech, Wuhan, China, 14695-1-AP) was performed following a standardized procedure, and the tissues were then analyzed under a Nikon Eclipse Ci microscope

While anecdotal evidence cannot substitute for controlled research, community observations provide a real-world perspective on outcomes

Areas with thinner skin, such as around the eyes or on the backs of hands, may show improvement earlier than areas with more significant laxity

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